I assume if you want to disable the normal keyboard navigation, you will have buttons to allow this kind of navigation.  You can keep a flag in your application named something like allowSelectedTabChanging and initialize it to False. Then handle the SelectedTabChanging event. If the flag is set to False, set e.Cancel on the event args to True. In your 'Next' and 'Previous' navigation buttons, set the flag to True, set the new selected tab and the se tthe flag back to False.