Hello smausa,

I tried to reproduce the issue in Initialize client side event  handler and btn_click.

In the both cases the contol was disabled and grayed out.

I used 10.3.20103.2120 and the latest service release 10.3.20103.2134 with the same result.

    <script type="text/javascript" id="igClientScript">

        function WebNumericEdit1_Initialize(oEdit, text) {

            //Add code to handle your event here.

           // oEdit.setEnabled(false);

        }

        function on_btnclick() {

            var ctrl = igedit_getById("WebNumericEdit1");

            ctrl.setEnabled(false);

        }

    </script>

<igtxt:WebNumericEdit ID="WebNumericEdit1" runat="server">

            <ClientSideEvents Initialize="WebNumericEdit1_Initialize" />

        </igtxt:WebNumericEdit>

        <input type="button" value="clickme" onclick=" return on_btnclick();" />

Can you please provide us with an isolated sample reproducing the issue?

Hope hearing from you.