I have my grid set up with a datasource pulling from an ADO .NET Entity Framework model. 

Controller

model.GridModel.DataSource = _db.InstrumentLists.Where(clause, SearchTerm)
                                                                .ToList<InstrumentList>()
                                                                .OrderBy(x => x.Tag)
                                                                .AsQueryable<InstrumentList>();

View

@( Html.Infragistics().Grid("InsrumentListGrid", Model.GridModel)

I am setting the DataSource and not the DataSourceUrl on purpose - all the paging, filtering and sorting is done client side.

The records that are pulled out depend on a search string, hence the Where clause.  If the result of the call is zero records, the grid crashes with a Null Reference Exception.

Here's the top of the stack:

[NullReferenceException: Object reference not set to an instance of an object.]
   Infragistics.Web.Mvc.GridModel.CheckNullables() +341
   Infragistics.Web.Mvc.GridModel.DataBind() +1173
   Infragistics.Web.Mvc.InfragisticsSuite`1.Grid(String id, IGridModel gridViewModel) +278
   ASP._Page_Views_InstrumentList_Index_cshtml.Execute() in c:\Users\DNatoli\Documents\Visual Studio 2010\Projects\ICMDB\ICMDB\Views\InstrumentList\Index.cshtml:39
   System.Web.WebPages.WebPageBase.ExecutePageHierarchy() +207
   System.Web.Mvc.WebViewPage.ExecutePageHierarchy() +81
   System.Web.WebPages.StartPage.RunPage() +19