Hello,

I have been looking into your question and prepared a small sample in order to demonstrate how such behavior could be achieved.
An approach I could suggest is to handle the grid's onColumnInit event. It would be fired for each column after the onInit and as an event argument is passed the initialized column, so you would have access to all of its properties.

In the event handler, you could check whether the data has values in this column and besed on this to set the column hidden property to true or false. For the purposes of the example, I'm logging the hidden column names in the cosole:

public onColumnInit(event: IgxColumnComponent) {
    const field = event.field;
    let isHidden = true;
    this.data.forEach(item => {
      if (item[field] !== null) {
        isHidden = false;
        return;
      }
    });
    if (isHidden) {
      console.log(event.field);
    }
    event.hidden = isHidden;
  }

Here could be found my sample for your reference. Please test it on your side and let me know if I may be of any further assistance.

Sincerely,
Teodosia Hristodorova
Associate Software Developer