Assuming you're using the grid's built-in pasting functionality you can
handle the BeforeClipboardOperation client side event and check if the
active cell belongs to the column where pasting is not allowed the
simply return true from the event handler.

function grdStatus_BeforeClipboardOperation(gridName, operationType,
options){
//Add code to handle your event here.
var grid = igtbl_getGridById(gridName);
if(operationType!=grid.eClipboardOperation.Paste)
return;
var activeCell = grid.getActiveCell();
if (activeCell && activeCell.Column.Key == "NoPastingColumn")
return true;
}